Primary Identifier | MGI:2146149 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 268780 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycosaminoglycan binding activity. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in basement membrane and interstitial matrix. Is active in photoreceptor ribbon synapse. Is expressed in hair follicle and rib. Orthologous to human EGFLAM (EGF like, fibronectin type III and laminin G domains). PHENOTYPE: Homozygous null mutants are viable and fertile under normal conditions. They exhibit abnormal photoreceptor ribbon synapses, resulting in alteration in synaptic signal transmission and visual function. [provided by MGI curators] |