Primary Identifier | MGI:107435 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 12563 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in synaptic membrane adhesion. Acts upstream of or within Notch signaling pathway. Located in plasma membrane. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Orthologous to human CDH6 (cadherin 6). PHENOTYPE: Mice homozygous for a null allele exhibit delayed mesenchyme to epithelial conversion and loss of nephrons. [provided by MGI curators] |