Primary Identifier | MGI:1915323 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 68073 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-lysine N-methyltransferase activity. Involved in several processes, including peptidyl-lysine trimethylation; positive regulation of proton-transporting ATP synthase activity, rotational mechanism; and positive regulation of sensory perception of pain. Predicted to be located in mitochondrial crista. Predicted to be active in mitochondrion. Is expressed in embryo. Orthologous to human ATPSCKMT (ATP synthase c subunit lysine N-methyltransferase). PHENOTYPE: Following carrageenan-induced priming, mice heterozygous for a null allele show a reduction in the magnitude of persistent prostaglandin E2-induced mechanical and thermal hyperalgesia. [provided by MGI curators] |