Primary Identifier | MGI:97424 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 18285 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein domain specific binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Located in manchette and outer dense fiber. Is expressed in parathyroid gland; testis; and thyroid gland. Orthologous to human ODF1 (outer dense fiber of sperm tails 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with asthenozoospermia, oligozoospermia, detached sperm head and absent acrosome reaction. Mice heterozygous for this allele exhibit asthenozoospermia without altered fertility. [provided by MGI curators] |