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Protein Coding Gene : Azin1 antizyme inhibitor 1
Primary Identifier  MGI:1859169 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  54375
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ornithine decarboxylase activator activity. Involved in positive regulation of polyamine transmembrane transport. Located in nucleus. Is expressed in embryo; extraembryonic component; pancreas epithelium; and placenta. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).
PHENOTYPE: Homozygous disruption of this gene results in neonatal lethality, a slight reduction in birth weight, and abnormal liver morphology. [provided by MGI curators]
  • synonyms:
  • MGI:1920775,
  • expressed sequence AI414949,
  • AI414949,
  • Oazin,
  • ornithine decarboxylase antizyme inhibitor,
  • MGI:2145992,
  • RIKEN cDNA 1700085L02 gene,
  • 1700085L02Rik,
  • Azin1,
  • ODC antizyme inhibitor,
  • Oazi,
  • antizyme inhibitor 1
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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