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Protein Coding Gene : Fbxo32 F-box protein 32
Primary Identifier  MGI:1914981 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  67731
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in response to denervation involved in regulation of muscle adaptation. Acts upstream of or within cellular response to dexamethasone stimulus. Located in Z disc and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; male reproductive gland or organ; and sensory organ. Orthologous to human FBXO32 (F-box protein 32).
PHENOTYPE: A targeted homozygous mutation in this gene results in resistance to skeletal muscle atrophy in response to nerve injury. [provided by MGI curators]
  • synonyms:
  • MGI:2146006,
  • MAFbx,
  • ATROGIN1,
  • Fbxo32,
  • atrogin-1,
  • RIKEN cDNA 4833442G10 gene,
  • AI430017,
  • 4833442G10Rik,
  • expressed sequence AI430017,
  • F-box protein 32
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

5 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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