| Primary Identifier | MGI:2681865 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 380993 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within hematopoietic progenitor cell differentiation and spongiotrophoblast layer development. Predicted to be located in nucleus. Is expressed in several structures, including extraembryonic component; nervous system; and placenta. Human ortholog(s) of this gene implicated in autoimmune thyroiditis. Orthologous to human ZFAT (zinc finger and AT-hook domain containing). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality associated with failure to initiation of embryo turning, abnormal embryonic hematopoiesis, abnormal spongiotrophoblast layer morphology, abnormal visceral yolk sac blood island morphology and pale yolk sac. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
