Primary Identifier | MGI:1345180 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 23936 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acetylcholine receptor inhibitor activity and ion channel inhibitor activity. Acts upstream of or within cholinergic synaptic transmission. Located in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; eye; and respiratory system. Orthologous to several human genes including LYNX1 (Ly6/neurotoxin 1). PHENOTYPE: Mice homozygous for a null allele exhibit increased sensitivity to nicotine, neurodegeneration, brain vacuoles amd improved cue-conditioned learning. [provided by MGI curators] |