| Primary Identifier | MGI:1098783 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 14787 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including focal adhesion assembly; glomerular filtration; and negative regulation of stress fiber assembly. Located in plasma membrane. Is expressed in several structures, including genitourinary system; hindlimb digit mesenchyme; musculoskeletal system; nervous system; and retina nuclear layer. Orthologous to human RHPN1 (rhophilin Rho GTPase binding protein 1). PHENOTYPE: Homozygous null mice are albuminuric, show podocyte foot process effacement, thickening of the glomerular basement membrane, and focal segmental glomerulosclerosis lesions. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
