Primary Identifier | MGI:1351660 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 27373 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase activity. Involved in several processes, including circadian regulation of gene expression; positive regulation of non-canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within negative regulation of Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and protein localization. Located in nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; nervous system; sensory organ; urinary system; and vibrissa. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to several human genes including CSNK1E (casein kinase 1 epsilon). PHENOTYPE: Mice homozygous for a null allele exhibit disruptions in circadian rhythms. [provided by MGI curators] |