| Primary Identifier | MGI:1196439 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 52609 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables chromatin binding activity; methylated histone binding activity; and single-stranded RNA binding activity. Acts upstream of or within sebaceous gland development. Located in nucleus. Part of PRC1 complex and heterochromatin. Is expressed in brain. Human ortholog(s) of this gene implicated in breast cancer; multiple myeloma; and myeloid leukemia. Orthologous to human CBX7 (chromobox 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased body length and develop liver and lung adenomas and carcinomas while mutant embryonic fibriblasts show a higher growth rate and reduced susceptibility to senescence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
