Primary Identifier | MGI:2180756 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 207911 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of calcium ion transport; and positive regulation of cytosolic calcium ion concentration. Located in ciliary membrane; neuron projection; and non-motile cilium. Is expressed in brain and lung. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1). PHENOTYPE: Homozygous mice for some alleles may display osteoporosis, resistance to diet-induced obesity, abnormal pyramidal neuron physiology, hyperactivity, polyphagia, increased heart rate and body temperature, sleep behavior, and impaired conditioned learning. [provided by MGI curators] |