Primary Identifier | MGI:3028590 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 74369 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Is expressed in brain; ovary; and testis. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human MEI1 (meiotic double-stranded break formation protein 1). PHENOTYPE: Homozygous mutant mice of both sexes exhibit meiotic defects and are infertile. [provided by MGI curators] |