Primary Identifier | MGI:1916279 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 69029 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable channel activator activity and protein-macromolecule adaptor activity. Predicted to be involved in calcium import into the mitochondrion and mitochondrial calcium ion homeostasis. Located in mitochondrion. Is expressed in nervous system; neural retina; orbito-sphenoid; and vibrissa. Orthologous to human SMDT1 (single-pass membrane protein with aspartate rich tail 1). PHENOTYPE: Mice homozygous for a null allele exhibit background sensitive preweaning lethality and impaired mitochondrial calcium uptake. [provided by MGI curators] |