Primary Identifier | MGI:2388651 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 223722 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable [acyl-carrier-protein] S-malonyltransferase activity. Predicted to be involved in fatty acid biosynthetic process and mitochondrial small ribosomal subunit assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT (malonyl-CoA-acyl carrier protein transacylase). PHENOTYPE: Mice homozygous for a conditional allele activated ubiquitously consume more food, fail to gain weight, are less physically active, and suffer from loss of white adipose tissue, reduced muscle strength, kyphosis, alopecia, hypothermia and shortened lifespan. [provided by MGI curators] |