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Protein Coding Gene : Tspo translocator protein

Primary Identifier  MGI:88222 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  12257
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables transmembrane transporter binding activity. Involved in negative regulation of metabolic process; positive regulation of reactive oxygen species metabolic process; and protein localization to mitochondrion. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; reproductive system; and sensory organ. Orthologous to human TSPO (translocator protein).
PHENOTYPE: Mice homozygous for a conditional allele activated in the male reproductive system exhibit normal testicular development, reproduction and testosterone production. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-1694,
  • benzodiazepine receptor, peripheral,
  • PBR,
  • Bzrp,
  • translocator protein,
  • Tspo1,
  • Tspo

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For