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Protein Coding Gene : Upk3a uroplakin 3A
Primary Identifier  MGI:98914 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  22270
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including potassium ion homeostasis; urea transport; and urinary bladder development. Located in apical plasma membrane. Is active in apical plasma membrane urothelial plaque. Is expressed in several structures, including alimentary system; genitourinary system; lung; notochord; and olfactory epithelium. Used to study vesicoureteral reflux. Orthologous to human UPK3A (uroplakin 3A).
PHENOTYPE: Homozygous null mice exhibit urogenital defects including abnormal urothelium, vesicoureteral reflux, and hydronephrosis. [provided by MGI curators]
  • synonyms:
  • Upk3a,
  • RIKEN cDNA 1110017C07 gene,
  • uroplakin 3,
  • MGD-MRK-15369,
  • Upk3,
  • 1110017C07Rik,
  • uroplakin 3A,
  • MGI:1915869
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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2 Driver For

Trail: ProteinCodingGene




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