Primary Identifier | MGI:1338786 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 18766 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium channel activity. Acts upstream of or within regulation of acrosome reaction. Located in sperm plasma membrane. Is expressed in cochlea. Orthologous to human PKDREJ (polycystin family receptor for egg jelly). PHENOTYPE: Homozygous null males are fertile in unrestricted mating trials but show lower reproductive success in sequential mating and artificial insemination trials. Although mutant sperm are able to capacitate in vitro, they acquire exocytotic competence at a slower rate than wild-type sperm. [provided by MGI curators] |