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Protein Coding Gene : Ttll8 tubulin tyrosine ligase-like family, member 8
Primary Identifier  MGI:1922902 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  239591
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein-glycine ligase activity, initiating. Involved in flagellated sperm motility and protein polyglycylation. Acts upstream of or within cilium assembly. Located in axoneme; microtubule cytoskeleton; and sperm flagellum. Orthologous to human TTLL8 (tubulin tyrosine ligase like 8).
PHENOTYPE: Mice homozygous for a null allele of Ttll8 and Ttll3 exhibit reduced male fertility associated with asthenozoospermia and kinked flagellum. [provided by MGI curators]
  • synonyms:
  • tubulin tyrosine ligase-like family, member 8,
  • RIKEN cDNA 1700019P01 gene,
  • 1700019P01Rik,
  • Ttll8
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3 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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Trail: ProteinCodingGene

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