| Primary Identifier | MGI:1289164 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 52683 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity. Involved in meiotic chromosome condensation; nuclear chromosome segregation; and regulation of chromosome segregation. Acts upstream of or within T cell differentiation in thymus. Located in condensed nuclear chromosome. Part of condensin complex. Is active in chromosome and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human NCAPH2 (non-SMC condensin II complex subunit H2). PHENOTYPE: Mice homozygous for an ENU-induced single point mutation display a specific defect in T cell development but are otherwise viable, fertile and overtly healthy with no apparent defects in B cell development. Homozygous null mice die before E12.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
