| Primary Identifier | MGI:108411 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 19082 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable adenyl ribonucleotide binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to contribute to AMP-activated protein kinase activity. Predicted to be involved in cellular response to glucose starvation; regulation of carbohydrate metabolic process; and regulation of catalytic activity. Located in nucleus. Is expressed in future brain; heart; liver; and nervous system. Orthologous to human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit hemolytic anemia, extramedullary hematopoiesis, and iron accumulation in the spleen, liver, and Kupffer cells. [provided by MGI curators] |