| Primary Identifier | MGI:1919643 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 72393 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium channel activity. Involved in cerebellar Purkinje cell differentiation; cerebellar granular layer development; and regulation of neuron apoptotic process. Acts upstream of or within negative regulation of apoptotic signaling pathway; negative regulation of neuron apoptotic process; and response to ischemia. Located in Golgi apparatus; endoplasmic reticulum; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and white fat. Orthologous to human FAIM2 (Fas apoptotic inhibitory molecule 2). PHENOTYPE: A mutation in this gene results in kidney abnormalities including enlargement and dilation. A reduced seizure threshold in response to pharmacological agents is also observed. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
