| Primary Identifier | MGI:106215 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 11830 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity and water channel activity. Acts upstream of or within camera-type eye morphogenesis; saliva secretion; and water transport. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and microvillus. Is expressed in several structures, including inner ear; lung; olfactory epithelium; salivary gland; and submandibular gland primordium. Used to study dry eye syndrome. Human ortholog(s) of this gene implicated in Bothnian type palmoplantar keratoderma. Orthologous to human AQP5 (aquaporin 5). PHENOTYPE: Homozygous null mutants exhibit reduced growth on solid food and secrete diminished amounts of hypertonic, viscous saliva. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
