| Primary Identifier | MGI:1194915 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 11419 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables monoatomic cation channel activity; monoatomic ion-gated channel activity; and pH-gated monoatomic ion channel activity. Involved in regulation of postsynapse assembly. Acts upstream of or within several processes, including behavioral fear response; learning or memory; and response to amphetamine. Located in synapse. Is active in glutamatergic synapse and plasma membrane. Is expressed in several structures, including brain. Orthologous to human ASIC1 (acid sensing ion channel subunit 1). PHENOTYPE: Homozygous mutation of this gene results in absence of H+-gated currents in hippocampal neurons, impaired long term potentiation, reduced excitatory postsynaptic potentials, and defective spatial learning and eye blink conditioning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
