| Primary Identifier | MGI:1860303 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 56149 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable PDZ domain binding activity; identical protein binding activity; and small GTPase binding activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within signal transduction. Located in plasma membrane. Is active in glutamatergic synapse. Orthologous to human TAMALIN (trafficking regulator and scaffold protein tamalin). PHENOTYPE: Mice homozygous for targeted null mutations develop and behave normally under ordinary conditions but display a marked reduction in sensitivity to acute morphine responses and impaired adaptive responses to morphine and cocaine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
