Primary Identifier | MGI:1915368 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 68118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and protein kinase binding activity. Involved in several processes, including autophagosome assembly; positive regulation of autophagy; and regulation of protein lipidation. Located in phagophore assembly site. Is expressed in adrenal gland. Orthologous to human ATG101 (autophagy related 101). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete lethality throughout fetal growth and development, smaller size and small and lipid-less alveolar lamellar bodies in type II pneumocytes. [provided by MGI curators] |