Primary Identifier | MGI:96704 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 110310 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in cytosol and intermediate filament cytoskeleton. Predicted to be active in keratin filament. Is expressed in several structures, including alimentary system; genitourinary system; sensory organ; skin; and trophectoderm. Orthologous to human KRT7 (keratin 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased cell proliferation of urothelial cells without histological evidence of hyperplasia. [provided by MGI curators] |