Primary Identifier | MGI:96616 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 16421 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable integrin binding activity. Acts upstream of or within T cell migration. Predicted to be part of integrin alpha4-beta7 complex. Predicted to be active in cell surface and focal adhesion. Is expressed in genitourinary system and thymus primordium. Orthologous to human ITGB7 (integrin subunit beta 7). PHENOTYPE: Homozygous null mice display hypoplasia of gut-associated lymph tissue due to defects in lymphocyte migration [provided by MGI curators] |