| Primary Identifier | MGI:96192 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 209448 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic limb morphogenesis; regionalization; and spinal cord motor neuron cell fate specification. Predicted to be located in nuclear body. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; intestine; limb; and spinal cord. Orthologous to human HOXC10 (homeobox C10). PHENOTYPE: Mice homozygous for a null allele exhibit skeletal transformations in thoracic, lumbar and sacral vertebrae, alterations in the pelvis and in the bones and ligaments of the hindlimb, femoral defects, decreased lumbar motor neuron and rib number, impairedcoordination, muscle wasting, and obesity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
