Primary Identifier | MGI:109372 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 12419 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in chromocenter; chromosomal region; and nucleolus. Part of histone deacetylase complex; histone methyltransferase complex; and transcription repressor complex. Is expressed in several structures, including alimentary system; early embryo; genitourinary system; nervous system; and sensory organ. Orthologous to human CBX5 (chromobox 5). PHENOTYPE: Mice homozygous for a mutation of this gene are viable and fertile and exhibit no apparent physical or behavioral abnormality. [provided by MGI curators] |