Primary Identifier | MGI:1921272 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 74022 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and chromatin binding activity. Predicted to be involved in transcription elongation-coupled chromatin remodeling and transcription initiation-coupled chromatin remodeling. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be part of nucleosome. Is expressed in several structures, including central nervous system; early conceptus; gonad; and retina. Used to study atrioventricular septal defect. Orthologous to human GLYR1 (glyoxylate reductase 1 homolog). PHENOTYPE: Homozygosity for a mutation of highly conserved proline 495 leads to the death of half of newborns within the first day. [provided by MGI curators] |