Primary Identifier | MGI:1918464 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 68606 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calmodulin-dependent protein phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in several processes, including positive regulation of cellular component biogenesis; protein dephosphorylation; and regulation of macromolecule metabolic process. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F). PHENOTYPE: Mice homozygous for a targeted mutation are not detected at weaning. Mice heterozygous for a targeted mutation display hyperactivity and an increase in pain threshold. [provided by MGI curators] |