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Protein Coding Gene : Tssk1 testis-specific serine kinase 1
Primary Identifier  MGI:1347557 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  22114
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables magnesium ion binding activity and protein serine/threonine kinase activity. Involved in peptidyl-serine phosphorylation and spermatid development. Located in motile cilium. Is expressed in embryo; seminiferous tubule; spermatid; and testis. Orthologous to several human genes including TSSK1B (testis specific serine kinase 1B).
PHENOTYPE: Male mice homozygous for a knock-out allele of Tssk1 and 2 are infertile due to arrested spermatogenesis. [provided by MGI curators]
  • synonyms:
  • testis-specific serine/threonine kinase,
  • Stk22a,
  • TSK-1,
  • MGI:99541,
  • Tssk1,
  • MGD-MRK-16319,
  • testis-specific serine kinase 1,
  • Tsk1,
  • serine/threonine kinase 22A (spermiogenesis associated),
  • Tssk
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