Primary Identifier | MGI:107854 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 27886 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in nervous system development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; face; and limb bud. Orthologous to human ESS2 (ess-2 splicing factor homolog). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality. Mice homozygous for a conditional allele activated in T cells exhibit reduced peripheral naive T cells and failure to maintain survival in response to IL-7. [provided by MGI curators] |