Primary Identifier | MGI:96269 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 19385 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to contribute to GTPase activator activity. Acts upstream of or within positive regulation of mitotic centrosome separation and spindle organization. Located in centrosome and cytoplasm. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; head mesenchyme; and sensory organ. Orthologous to human RANBP1 (RAN binding protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal growth retardation, decreased body weight, impaired spermatogenesis, and male infertility. [provided by MGI curators] |