| Primary Identifier | MGI:1298405 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 11773 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables disordered domain specific binding activity. Involved in clathrin-dependent endocytosis and postsynaptic neurotransmitter receptor internalization. Located in mitochondrion. Part of AP-2 adaptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human AP2M1 (adaptor related protein complex 2 subunit mu 1). PHENOTYPE: Mice homozygous for a targeted deletion display embryonic lethality before implantation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
