| Primary Identifier | MGI:2146636 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 94175 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables serine-type endopeptidase inhibitor activity. Involved in several processes, including defense response to other organism; negative regulation of blood vessel endothelial cell migration; and positive regulation of blood vessel remodeling. Acts upstream of or within negative regulation of fibrinolysis. Located in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in thrombophilia due to HRG deficiency and thrombosis. Orthologous to human HRG (histidine rich glycoprotein). PHENOTYPE: Mice homozygous for a null mutation display mild monocytosis, decreased bleeding time, faster clot lysis, and abnormal blood coagulation; however, wound healing is normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
