| Primary Identifier | MGI:88056 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 11815 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cholesterol binding activity. Involved in negative regulation of lipoprotein lipid oxidation and response to reactive oxygen species. Predicted to be located in several cellular components, including cytosolic ribosome; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human APOD (apolipoprotein D). PHENOTYPE: Mice homozygous for one null allele display increased sensitivity to reactive oxygen species, impaired motor and spatial learning, and decreased vertical and horizontal activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
