Primary Identifier | MGI:1353421 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 30060 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable iron ion binding activity. Predicted to be involved in several processes, including negative regulation of substrate adhesion-dependent cell spreading; positive regulation of extracellular matrix disassembly; and positive regulation of plasminogen activation. Predicted to be located in cell surface. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; integumental system; and sensory organ. Orthologous to human MELTF (melanotransferrin). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile, exhibit no physical defects, and develop normally with no detectable alterations in iron metabolism. [provided by MGI curators] |