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Protein Coding Gene : Sema5b sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Primary Identifier  MGI:107555 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  20357
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Acts upstream of or within axon extension; detection of light stimulus involved in visual perception; and neuron projection guidance. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; future brain; genitourinary system; and trunk connective tissue. Orthologous to human SEMA5B (semaphorin 5B).
PHENOTYPE: Mice homozygous for a null mutation display defects in neurite arborization of multiple retinal cell types. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-36126,
  • AI893641,
  • SemG,
  • semaphorin G,
  • Semag,
  • mKIAA1445,
  • Sema5b,
  • expressed sequence AI893641,
  • MGI:2146519,
  • sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
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