Primary Identifier | MGI:1337040 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 18171 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Acts upstream of or within positive regulation of gene expression. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; ear; genitourinary system; liver; and nervous system. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2). PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but exhibit specific loss of xenoregulation of CYP3A11. [provided by MGI curators] |