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Protein Coding Gene : Phldb2 pleckstrin homology like domain, family B, member 2
Primary Identifier  MGI:2444981 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  208177
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in cell migration and establishment of cell polarity. Predicted to be located in several cellular components, including cell leading edge; cytoskeleton; and cytosol. Predicted to be active in basal cortex. Predicted to colocalize with focal adhesion. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human PHLDB2 (pleckstrin homology like domain family B member 2).
PHENOTYPE: Mice homozygous for a conditional allele activated in neurons exhibit impaired LTP. [provided by MGI curators]
  • synonyms:
  • pleckstrin homology like domain, family B, member 2,
  • LL5b,
  • expressed sequence AV253284,
  • MGI:2146603,
  • AV253284,
  • Phldb2,
  • C820004H04Rik,
  • RIKEN cDNA C820004H04 gene,
  • LL5beta
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