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Protein Coding Gene : Dppa4 developmental pluripotency associated 4
Primary Identifier  MGI:2157525 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  73693
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable chromatin binding activity. Acts upstream of or within lung-associated mesenchyme development. Located in nucleus. Is expressed in several structures, including blastocyst; early embryo; foregut; gonad; and nose. Orthologous to human DPPA4 (developmental pluripotency associated 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit perinatal and postnatal lethality, abnormal lung morphology, skeletal defects, and a maternal effect on female fertility. [provided by MGI curators]
  • synonyms:
  • expressed sequence C76608,
  • MGI:1920943,
  • Dppa4,
  • C76608,
  • 2410091M23Rik,
  • MGI:2146696,
  • RIKEN cDNA 2410091M23 gene,
  • developmental pluripotency associated 4,
  • ECAT15-1
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