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Protein Coding Gene : Cip2a cell proliferation regulating inhibitor of protein phosphatase 2A
Primary Identifier  MGI:2146335 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  224171
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein homodimerization activity and protein phosphatase inhibitor activity. Acts upstream of or within positive regulation of neuroblast proliferation and spermatogenesis. Predicted to be located in cytosol and plasma membrane. Predicted to be active in chromosome. Is expressed in brain subventricular zone; hindlimb interdigital region; skin; and telencephalon. Orthologous to human CIP2A (cellular inhibitor of PP2A).
PHENOTYPE: Mice homozygous for a hypomorphic allele display oligozoospermia, small epididymis and impaired spermatogonial progenitor cell maintenance. [provided by MGI curators]
  • synonyms:
  • Cip2a,
  • AA408511,
  • MGI:2146550,
  • RIKEN cDNA C330027C09 gene,
  • expressed sequence AA408511,
  • C330027C09Rik,
  • cell proliferation regulating inhibitor of protein phosphatase 2A,
  • MGI:6154701,
  • expressed sequence AU018569,
  • AU018569
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