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Protein Coding Gene : St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Primary Identifier  MGI:1888707 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  54613
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable N-acetyllactosaminide alpha-2,3-sialyltransferase activity and beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Predicted to be involved in cellular response to interleukin-6; glycolipid biosynthetic process; and protein glycosylation. Predicted to be located in Golgi membrane. Is expressed in dentate gyrus subgranular zone and early tubule. Orthologous to human ST3GAL6 (ST3 beta-galactoside alpha-2,3-sialyltransferase 6).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit modest impairment in leukocyte rolling and neutrophil recruitment. [provided by MGI curators]
  • synonyms:
  • MGI:1922763,
  • RIKEN cDNA 1700023B24 gene,
  • 1700023B24Rik,
  • Siat10,
  • sialyltransferase 10 (alpha-2,3-sialyltransferase VI),
  • expressed sequence AW552396,
  • St3gal6,
  • expressed sequence AI930218,
  • MGI:2146521,
  • AI930218,
  • ST3Gal VI,
  • ST3 beta-galactoside alpha-2,3-sialyltransferase 6,
  • AW552396,
  • MGI:2146659
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