| Primary Identifier | MGI:99612 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 13837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ephrin receptor activity and growth factor binding activity. Involved in several processes, including axonal fasciculation; ephrin receptor signaling pathway; and synaptic membrane adhesion. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus; negative regulation of neuron projection development; and regulation of cell migration. Is active in GABA-ergic synapse and presynapse. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3). PHENOTYPE: Mice homozygous for disruptions in this gene usually die within 48 hours of birth of cardiac failure. Survivors develop normally with no indications of cardiac abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
