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Protein Coding Gene : Ltn1 listerin E3 ubiquitin protein ligase 1
Primary Identifier  MGI:1926163 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  78913
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ubiquitin protein ligase activity. Involved in protein autoubiquitination. Predicted to be part of RQC complex. Predicted to be active in cytosolic ribosome. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human LTN1 (listerin E3 ubiquitin protein ligase 1).
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Mice homozygous for a point mutation display progressive neuron degeneration and age dependent motor deficits. [provided by MGI curators]
  • synonyms:
  • 4930528H02Rik,
  • expressed sequence AV266914,
  • Zfp294,
  • Rnf160,
  • MGI:2146728,
  • Ltn1,
  • C87237,
  • listerin E3 ubiquitin protein ligase 1,
  • MGI:2146604,
  • RIKEN cDNA 4930528H02 gene,
  • expressed sequence C87237,
  • Listerin,
  • ring finger protein 160,
  • zinc finger protein 294,
  • AV266914
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Features --> Cross References

Genome

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3 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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