| Primary Identifier | MGI:2652030 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 239931 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable channel activity; identical protein binding activity; and paracellular tight junction channel activity. Predicted to be involved in several processes, including bicellular tight junction assembly; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; and paracellular transport. Located in tight junction. Is expressed in several structures, including branchial arch; genitourinary system; gut; sensory organ; and surface ectoderm. Orthologous to human CLDN17 (claudin 17). PHENOTYPE: Homozygous null mice exhibit kidney damage and oxidative stress in the kidney, electrolyte imbalance, hypophagia, polydipsia, constipation, and an early delay in growth but reach normal size by 8-18 weeks. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
