Primary Identifier | MGI:97509 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 18546 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calmodulin binding activity. Predicted to be involved in several processes, including negative regulation of neuron apoptotic process; positive regulation of CAMKK-AMPK signaling cascade; and positive regulation of dopamine secretion. Predicted to be located in axon and neurofilament. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human PCP4 (Purkinje cell protein 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired motor learning and abnormal synaptic plasticity. [provided by MGI curators] |