Primary Identifier | MGI:1344338 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 24001 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of axonogenesis and small GTPase-mediated signal transduction. Located in cytoplasm and membrane. Is expressed in several structures, including cartilage; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2). PHENOTYPE: Mcie heterozygous for a knock-out allele exhibit reduced transmission of the t-haplotype. [provided by MGI curators] |